粉末冶金温压工艺的研究进展及其展望

综述了粉末冶金温压工艺的研究进展,概述了温压工艺的粉末原料、聚合物、温度、压力、烧结环节对温压工艺的影响和温压工艺的致密化机理。详细介绍了温压工艺的新进展—流动温压、高压温压等,并对其应用前景进行了展望。     

某地铁站中央空调空调水系统节能技术改造方案

本文针对某地铁站中央空调水系统工程分析了目前系统中水泵的能耗起因，并提出了改造水泵降低能耗的具体方法，与改造前系统水泵能耗相比降低了56％。     

先秦汉语中的“所为”结构分析

以十三经为调查对象,穷尽性地检索了"所为"及其相关结构的用例;对"所为"、"所为"相关结构以及二者带动词的语法语用功能作了细致详尽的探讨,梳理出了"所为"及其相关结构的意义和用法.     

基于Rough Set理论对原棉纱线强度的规则提取

纱线的强度和纤维的性能之间存在复杂的关系．利用纤维特性等级对实验所得的纱线强度和纤维性能的数据进行离散化处理，结合Rough Set理论知识，计算不同的纤维性能对纱线强度的影响因子，再基于约简后的离散化数据。提取数据中潜在的纱线强度和纤维性能之间的知识规则。     

The development of adaptive body reactions after intensive physical loading]

The dependence between the activity parameters of muscarine antagonists in the prevention of haloperidol catalepsy in rats and those in tests characterizing the interaction of ligands and various subtypes of m-cholinoceptors was studied. It was established by constructing the mathematical dependence that blockade of m1-cholinoceptors increases, while that of m2-cholinoceptors reduces the antiparkinsonian activity of the drugs. The activity of the muscarine antagonist pentiphan in the prevention of haloperidol-induced catalepsy in rats exceeds the activity of such traditional antiparkinsonian drugs as cyclodol and amedin.     

Spermatogenesis and the testosterone level in young male silver foxes in their reproductive period

15.7% of spermatozoa were found to be abnormal in silver fox males during their first reproductive season. The total number of spermatozoa and the abnormal spermatogenesis remained unchanged during mating season. Sexual stimulation increased the testosterone level only at the beginning of the mating season.     

Functional analysis of the amino- and carboxyl-termini of streptokinase

1. The classical ATP sensitive K+ (K(ATP)) channels are composed of a sulphonylurea receptor (SUR) and an inward rectifying K+ channel subunit (BIR/Kir6.2). They are the targets of vasorelaxant agents called K+ channel openers, such as pinacidil and nicorandil. 2. In order to examine the tissue selectivity of pinacidil and nicorandil, in vitro, we compared the effects of these agents on cardiac type (SUR2A/Kir6.2) and vascular smooth muscle type (SUR2B/Kir6.2) of the K(ATP) channels heterologously expressed in HEK293T cells, a human embryonic kidney cell line, by using the patch-clamp method. 3. In the cell-attached recordings (145 mM K+ in the pipette), pinacidil and nicorandil activated a weakly inwardly-rectifying, glibenclamide-sensitive 80 pS K+ channel in both the transfected cells. 4. In the whole-cell configuration, pinacidil showed a similar potency in activating the SUR2B/Kir6.2 and SUR2A/Kir6.2 channels (EC50 of approximately 2 and approximately 10 microM, respectively). On the other hand, nicorandil activated the SUR2B/Kir6.2 channel > 100 times more potently than the SUR2A/Kir6.2 (EC50 of approximately 10 microM and > 500 microM, respectively). 5. Thus, nicorandil, but not pinacidil, preferentially activates the K(ATP) channels containing SUR2B. Because SUR2A and SUR2B are diverse only in 42 amino acids at their C-terminal ends, it is strongly suggested that this short part of SUR2B may play a critical role in the action of nicorandil on the vascular type classical K(ATP) channel.     

“中国式”非显形奢华

奢侈品在中国逐渐成为热门产业,建立在精神层面上的“非显形奢华”也渐为众人关注。中国拥有深厚的文化底蕴,足以创造撼动视觉新体验的新“奢华”美学。当创意市场不断推进,变得成熟之后,中国的“非显形奢华”定会有更高的价值,奢华不再是炫耀身份的代名词,而是融合民族特色、具有独特的设计品位,真正意义上的顶级产品或服务,是一种低调、内敛、优雅的“非显形奢华”。     

Palliative chemotherapy with CMF after the same adjuvant regimen for breast cancer. The Breast Cancer Study Group

BACKGROUND: The results of palliative chemotherapy with cyclophosphamide, methotrexate and 5-fluorouracil (CMF) in patients with advanced breast cancer who received adjuvant therapy with the same regimen were investigated. RESULTS: Of 47 patients, 14 (30%) achieved an objective remission (median duration 9.5, range 5-21 months) and 8 (17%) stabilisation of disease (median duration 6, range 3-17 months). Objective remissions were observed in premenopausal as well as in postmenopausal women, in patients with all categories of dominant localisation of disease and regardless of the oestradiol receptor status of the primary tumour or eventual previous endocrine therapy. One of 4 and 13 of 43 patients who started palliative chemotherapy within or later than 12 months after the last adjuvant course obtained an objective remission. The median survival time from start of therapy of all treated patients was 12 (range 1-40) months. Patients with an objective remission or stable disease and patients with progressive disease had a median survival time of 20 (range 6-40) and 6 (range 1-35) months respectively (p < 0.0001). CONCLUSIONS: Palliative treatment with CMF should not be rejected for patients who have relapsed after adjuvant chemotherapy with the same modality.